2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-22 Isoform
  6. IL-22 Agonist

IL-22 Agonist

IL-22 Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-147128
    PY109
    		Agonist 99.15%
    PY109 is an orally active and highly selective aryl hydrocarbon receptor (AHR) agonist. PY109's EC50 values in human-derived HepG2 and mouse Hepa-1c1c7 cells are 1.2 nM and 1.4 nM respectively. PY109 significantly upregulates the expression of CYP1A1 and IL-22, and inhibits the expression of IL-17A. PY109 significantly improves colitis in mice. PY109 can be used for research on colitis.